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PAI‐1 induces Src inhibitor resistance via CCL5 in HER2‐positive breast cancer cells

Tyrosine kinase Src is overexpressed and activated in various tumors, including breast cancer, and is supposed to promote cancer formation and development. Src inhibitors have been developed recently and have shown efficacy in breast cancer as a single agent or in combination with anti‐HER2 antibodi...

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Detalles Bibliográficos
Autores principales: Fang, Hehui, Jin, Juan, Huang, Doudou, Yang, Fang, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989873/
https://www.ncbi.nlm.nih.gov/pubmed/29601121
http://dx.doi.org/10.1111/cas.13593