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The double‐edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation

BACKGROUND: Sarcopenia is the age‐related degeneration characterized with the decline of skeletal muscle mass, strength, and function. The imbalance of protein synthesis and degradation which jeopardizes immune, hormone regulation, and muscle‐motor neuron connection is the main cause of sarcopenia....

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Detalles Bibliográficos
Autores principales: Jheng, Jia‐Rong, Chen, Yuan‐Siao, Ao, Un Iong, Chan, Ding‐Cheng, Huang, Jenq‐Wen, Hung, Kuang‐Yu, Tarng, Der‐Cheng, Chiang, Chih‐Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989876/
https://www.ncbi.nlm.nih.gov/pubmed/29380555
http://dx.doi.org/10.1002/jcsm.12288