Nanoparticles with high payloads of pipemidic acid, a poorly soluble crystalline drug: drug-initiated polymerization and self-assembly approach

Nowadays, biodegradable polymers such as poly(lactic acid) (PLA), poly(D,L-lactic-co-glycolic acid) (PLGA) and poly(ε-caprolactone) (PCL) remain the most common biomaterials to produce drug-loaded nanoparticles (NPs). Pipemidic acid (PIP) is a poorly soluble antibiotic with a strong tendency to crys...

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Detalles Bibliográficos
Autores principales: Pancani, Elisabetta, Menendez-Miranda, Mario, Pastor, Alexandra, Brisset, François, Bernet-Camard, Marie-Françoise, Desmaële, Didier, Gref, Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989915/
https://www.ncbi.nlm.nih.gov/pubmed/29881681
http://dx.doi.org/10.1016/j.apsb.2018.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989915/
https://www.ncbi.nlm.nih.gov/pubmed/29881681
http://dx.doi.org/10.1016/j.apsb.2018.03.008

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