Cargando…

Nanoparticles with high payloads of pipemidic acid, a poorly soluble crystalline drug: drug-initiated polymerization and self-assembly approach

Nowadays, biodegradable polymers such as poly(lactic acid) (PLA), poly(D,L-lactic-co-glycolic acid) (PLGA) and poly(ε-caprolactone) (PCL) remain the most common biomaterials to produce drug-loaded nanoparticles (NPs). Pipemidic acid (PIP) is a poorly soluble antibiotic with a strong tendency to crys...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pancani, Elisabetta, Menendez-Miranda, Mario, Pastor, Alexandra, Brisset, François, Bernet-Camard, Marie-Françoise, Desmaële, Didier, Gref, Ruxandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989915/ https://www.ncbi.nlm.nih.gov/pubmed/29881681 http://dx.doi.org/10.1016/j.apsb.2018.03.008

Ejemplares similares

Degradation of Polymer-Drug Conjugate Nanoparticles Based on Lactic and Itaconic Acid
por: Vuong, Mai Dang Le, et al.
Publicado: (2022)

Evolution of the Computational Pharmaceutics Approaches in the Modeling and Prediction of Drug Payload in Lipid and Polymeric Nanocarriers
por: Abd-algaleel, Shaymaa A., et al.
Publicado: (2021)

Synthesis and in vitro antimicrobial activity screening of new pipemidic acid derivatives
por: Popiołek, Łukasz, et al.
Publicado: (2018)

Remote Loading: The Missing Piece for Achieving High Drug Payload and Rapid Release in Polymeric Microbubbles
por: Rastegar, Ghazal, et al.
Publicado: (2023)

Antibody–drug conjugates: Recent advances in payloads
por: Wang, Zhijia, et al.
Publicado: (2023)

Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes
por: C. Alves, Paula, et al.
Publicado: (2020)

Single particle optical extinction and scattering allows real time quantitative characterization of drug payload and degradation of polymeric nanoparticles
por: Potenza, M. A. C., et al.
Publicado: (2015)

β-Cyclodextrin Inclusion Complex to Improve Physicochemical Properties of Pipemidic Acid: Characterization and Bioactivity Evaluation
por: Iacovino, Rosa, et al.
Publicado: (2013)

An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance
por: Abed, Nadia, et al.
Publicado: (2015)

Antibody-Drug Conjugates Containing Payloads from Marine Origin
por: Cheng-Sánchez, Iván, et al.
Publicado: (2022)

Nanosized Drug Delivery Systems to Fight Tuberculosis
por: Bourguignon, Tom, et al.
Publicado: (2023)

Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance
por: Yamazaki, Chisato M., et al.
Publicado: (2021)

Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates
por: Karpov, Alexei S., et al.
Publicado: (2018)

Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release
por: Quintana, Jeremy M., et al.
Publicado: (2022)

Payload diversification: a key step in the development of antibody–drug conjugates
por: Conilh, Louise, et al.
Publicado: (2023)

Disulfide re-bridging reagents for single-payload antibody-drug conjugates
por: King, Thomas A., et al.
Publicado: (2023)

Aptamers with Self-Loading Drug Payload and pH-Controlled Drug Release for Targeted Chemotherapy
por: Zeng, Zihua, et al.
Publicado: (2021)

A New Approach for Improving the Antibacterial and Tumor Cytotoxic Activities of Pipemidic Acid by Including It in Trimethyl-β-cyclodextrin
por: Lavorgna, Margherita, et al.
Publicado: (2019)

Compartmentalized Polymeric Nanoparticles Deliver Vancomycin in a pH-Responsive Manner
por: Ural, Merve Seray, et al.
Publicado: (2021)

Lung Surfactant Microbubbles Increase Lipophilic Drug Payload for Ultrasound-Targeted Delivery
por: Sirsi, Shashank R., et al.
Publicado: (2013)

Challenges and opportunities to develop enediyne natural products as payloads for antibody-drug conjugates
por: Adhikari, Ajeeth, et al.
Publicado: (2021)

Near-Infrared-Induced Heating of Confined Water in Polymeric Particles for Efficient Payload Release
por: Viger, Mathieu L., et al.
Publicado: (2014)

Polymeric Microspheres Designed to Carry Crystalline Drugs at Their Surface or Inside Cavities and Dimples
por: Shen, Meitong, et al.
Publicado: (2023)

Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan
por: He, Yuanzhi, et al.
Publicado: (2019)

Solid-State NMR Spectroscopy: A Key Tool to Unravel the Supramolecular Structure of Drug Delivery Systems
por: Porcino, Marianna, et al.
Publicado: (2021)

Adnectin–drug conjugates for Glypican-3-specific delivery of a cytotoxic payload to tumors
por: Lipovšek, Daša, et al.
Publicado: (2018)

Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility
por: Satomaa, Tero, et al.
Publicado: (2018)

Antibody-Drug Conjugates in Solid Tumor Oncology: An Effectiveness Payday with a Targeted Payload
por: Kondrashov, Aleksei, et al.
Publicado: (2023)

Novel self assembling nanoparticles for the oral administration of fondaparinux: Synthesis, characterization and in vivo evaluation
por: Ralay-Ranaivo, Bettina, et al.
Publicado: (2014)

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis
por: Machelart, Arnaud, et al.
Publicado: (2019)

Drug-Loaded Polymeric Particulated Systems for Ophthalmic Drugs Release
por: Mihailovici, Ruxandra, et al.
Publicado: (2022)

Cheminformatics-driven discovery of polymeric micelle formulations for poorly soluble drugs
por: Alves, Vinicius M., et al.
Publicado: (2019)

Soluplus(®) polymeric nanomicelles improve solubility of BCS-class II drugs
por: Pignatello, Rosario, et al.
Publicado: (2022)

Synthesis, spectroscopic, thermal, antimicrobial and electrochemical characterization of some novel Ru(iii), Pt(iv) and Ir(iii) complexes of pipemidic acid
por: Alibrahim, Khuloud A., et al.
Publicado: (2018)

A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy
por: Böhnke, Niels, et al.
Publicado: (2022)

Huygens: science, payload and mission
por: Wilson, A
Publicado: (1997)

Satellite communications payload and system
por: Braun, T M
Publicado: (2012)

Acetic Acid-Modulated Room Temperature Synthesis of MIL-100 (Fe) Nanoparticles for Drug Delivery Applications
por: Ding, Mengli, et al.
Publicado: (2023)

Polymeric Micelles, a Promising Drug Delivery System to Enhance Bioavailability of Poorly Water-Soluble Drugs
por: Xu, Wei, et al.
Publicado: (2013)

Thermodynamic Correlation between Liquid–Liquid Phase Separation and Crystalline Solubility of Drug-Like Molecules
por: Uekusa, Taiga, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p7n61rbla35l3fr36s1gn2vcf4