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Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire

Eliciting broad and potent HIV-specific neutralizing antibody responses represents the holy grail of HIV vaccine efforts. Data from singly infected individuals with broad and potent plasma neutralizing activity targeting one epitope have guided our understanding of how these responses develop. Howev...

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Detalles Bibliográficos
Autores principales: Williams, Katherine L., Wang, Bingjie, Arenz, Dana, Williams, James A., Dingens, Adam S., Cortez, Valerie, Simonich, Cassandra A., Rainwater, Stephanie, Lehman, Dara A., Lee, Kelly K., Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990032/
https://www.ncbi.nlm.nih.gov/pubmed/29669274
http://dx.doi.org/10.1016/j.celrep.2018.03.082