Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

We introduce a new class of semisynthetic fluorescent biosensors for the quantification of free nicotinamide adenine dinucleotide (NAD(+)) and ratios of reduced to oxidized nicotinamide adenine dinucleotide phosphate (NADPH/NADP(+)) in live cells. Sensing is based on controlling the spatial proximit...

Descripción completa

Detalles Bibliográficos
Autores principales: Sallin, Olivier, Reymond, Luc, Gondrand, Corentin, Raith, Fabio, Koch, Birgit, Johnsson, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990361/
https://www.ncbi.nlm.nih.gov/pubmed/29809136
http://dx.doi.org/10.7554/eLife.32638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990361/
https://www.ncbi.nlm.nih.gov/pubmed/29809136
http://dx.doi.org/10.7554/eLife.32638

Ejemplares similares