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A novel functional polymorphism of GFAP decrease glioblastoma susceptibility through inhibiting the binding of miR-139

Glioblastoma (GBM) is the most commonly diagnosed solid tumor outside the central nervous system. However, genetic factors underlying GBM remain largely unclear. Previous studies indicated that Glial fibrillary acidic protein (GFAP) might play an important role in the aggressiveness of GBM and also...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Wang, Ming-Lei, Wang, Chang-Hui, Sun, Shu-Yan, Zhang, Han-Bing, Jiang, Yang-Yang, Xu, Qi-Wu, Wang, Ying, Gu, Shi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990380/
https://www.ncbi.nlm.nih.gov/pubmed/29746255
http://dx.doi.org/10.18632/aging.101442