Accurate detection of complex structural variations using single molecule sequencing

Structural variations (SVs) are the largest source of genetic variation, but remain poorly understood because of limited genomics technology. Single molecule long-read sequencing from Pacific Biosciences and Oxford Nanopore has the potential to dramatically advance the field, although their high err...

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Detalles Bibliográficos
Autores principales: Sedlazeck, Fritz J., Rescheneder, Philipp, Smolka, Moritz, Fang, Han, Nattestad, Maria, von Haeseler, Arndt, Schatz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990442/
https://www.ncbi.nlm.nih.gov/pubmed/29713083
http://dx.doi.org/10.1038/s41592-018-0001-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990442/
https://www.ncbi.nlm.nih.gov/pubmed/29713083
http://dx.doi.org/10.1038/s41592-018-0001-7

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