Picky Comprehensively Detects High Resolution Structural Variants in Nanopore Long Reads

Acquired genomic structural variants (SVs) are major hallmarks of the cancer genome, but they are challenging to reconstruct from short-read sequencing data. Here, we exploit the long-reads of the nanopore platform using our customized pipeline, Picky (https://github.com/TheJacksonLaboratory/Picky),...

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Detalles Bibliográficos
Autores principales: Gong, Liang, Wong, Chee-Hong, Cheng, Wei-Chung, Tjong, Harianto, Menghi, Francesca, Ngan, Chew Yee, Liu, Edison T., Wei, Chia-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990454/
https://www.ncbi.nlm.nih.gov/pubmed/29713081
http://dx.doi.org/10.1038/s41592-018-0002-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990454/
https://www.ncbi.nlm.nih.gov/pubmed/29713081
http://dx.doi.org/10.1038/s41592-018-0002-6

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