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Picky Comprehensively Detects High Resolution Structural Variants in Nanopore Long Reads
Acquired genomic structural variants (SVs) are major hallmarks of the cancer genome, but they are challenging to reconstruct from short-read sequencing data. Here, we exploit the long-reads of the nanopore platform using our customized pipeline, Picky (https://github.com/TheJacksonLaboratory/Picky),...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990454/ https://www.ncbi.nlm.nih.gov/pubmed/29713081 http://dx.doi.org/10.1038/s41592-018-0002-6 |