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Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis

Epidemiological studies have demonstrated an increased leukemia incidence following ionizing radiation exposure, but to date, the target cells and underlying mechanisms of radiation leukemogenesis remain largely unidentified. We engineered a mouse model carrying a different fluorescent marker on eac...

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Detalles Bibliográficos
Autores principales: Verbiest, Tom, Finnon, Rosemary, Brown, Natalie, Cruz-Garcia, Lourdes, Finnon, Paul, O’Brien, Grainne, Ross, Eleanor, Bouffler, Simon, Scudamore, Cheryl L., Badie, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990525/
https://www.ncbi.nlm.nih.gov/pubmed/29556020
http://dx.doi.org/10.1038/s41375-018-0085-1