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Integrin β1 Optimizes Diabetogenic T Cell Migration and Function in the Pancreas

T cell search behavior is dictated by their need to encounter their specific antigen to eliminate target cells. However, mechanisms controlling effector T cell motility are highly tissue-dependent. Specifically, how diabetogenic T cells encounter their target beta cells in dispersed islets throughou...

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Detalles Bibliográficos
Autores principales: Espinosa-Carrasco, Gabriel, Le Saout, Cécile, Fontanaud, Pierre, Michau, Aurélien, Mollard, Patrice, Hernandez, Javier, Schaeffer, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990596/
https://www.ncbi.nlm.nih.gov/pubmed/29904378
http://dx.doi.org/10.3389/fimmu.2018.01156