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Neuroprotective Effects of Proanthocyanidins, Natural Flavonoids Derived From Plants, on Rotenone-Induced Oxidative Stress and Apoptotic Cell Death in Human Neuroblastoma SH-SY5Y Cells

Proanthocyanidins (PA) are natural flavonoids widely present in many vegetables, fruits, nuts and seeds, and especially in grape seed. In the present study, we examined the neuroprotective effects of PA and the underlying molecular mechanism in rotenone model of Parkinson's disease (PD). We fou...

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Detalles Bibliográficos
Autores principales: Ma, Jian, Gao, Shan-Shan, Yang, Hai-Jie, Wang, Mian, Cheng, Bin-Feng, Feng, Zhi-Wei, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990600/
https://www.ncbi.nlm.nih.gov/pubmed/29904339
http://dx.doi.org/10.3389/fnins.2018.00369