CDK4/6 and PDGFRA Signaling as Therapeutic Targets in Diffuse Intrinsic Pontine Glioma

Diffuse intrinsic pontine gliomas (DIPGs) are incurable childhood brain tumors, whereby the standard of care is focal radiation, a treatment that provides temporary relief for most patients. Surprisingly, decades of clinical trials have failed to identify additional therapies that can prolong surviv...

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Detalles Bibliográficos
Autores principales: Hoeman, Christine, Shen, Chen, Becher, Oren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990603/
https://www.ncbi.nlm.nih.gov/pubmed/29904623
http://dx.doi.org/10.3389/fonc.2018.00191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990603/
https://www.ncbi.nlm.nih.gov/pubmed/29904623
http://dx.doi.org/10.3389/fonc.2018.00191

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