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The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells

BACKGROUND: T follicular helper (Tfh) cells are key players in the production of antibody-producing B cells via the germinal center reaction. Therapeutic strategies targeting Tfh cells are important where antibody formation is implicated in disease, such as transplant rejection and autoimmune diseas...

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Detalles Bibliográficos
Autores principales: Wallin, Elizabeth F., Hill, Danika L., Linterman, Michelle A., Wood, Kathryn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990622/
https://www.ncbi.nlm.nih.gov/pubmed/29904381
http://dx.doi.org/10.3389/fimmu.2018.01184