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The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells
BACKGROUND: T follicular helper (Tfh) cells are key players in the production of antibody-producing B cells via the germinal center reaction. Therapeutic strategies targeting Tfh cells are important where antibody formation is implicated in disease, such as transplant rejection and autoimmune diseas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990622/ https://www.ncbi.nlm.nih.gov/pubmed/29904381 http://dx.doi.org/10.3389/fimmu.2018.01184 |