A Tumor-Specific Tissue-Penetrating Peptide Enhances the Efficacy of Chemotherapy Drugs in Gastric Cancer

PURPOSE: C-end rule (CendR) peptides are found to enhance the penetration of chemotherapeutic agents into tumor cells, while GX1 is a peptide that homes to gastric cancer (GC) vasculature. This study aimed to synthesize a novel peptide GX1-RPAKPAR (GXC) and to explore the effect of GXC on sensitizin...

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Detalles Bibliográficos
Autores principales: Jin, Zhian, Wang, Pujie, Chen, Jie, He, Li, Xiao, Lijia, Yong, Kaisen, Deng, Shenglin, Zhou, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990678/
https://www.ncbi.nlm.nih.gov/pubmed/29869457
http://dx.doi.org/10.3349/ymj.2018.59.5.595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990678/
https://www.ncbi.nlm.nih.gov/pubmed/29869457
http://dx.doi.org/10.3349/ymj.2018.59.5.595

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