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CpG Island Methylator Phenotype and Methylation of Wnt Pathway Genes Together Predict Survival in Patients with Colorectal Cancer

PURPOSE: Dysregulation of the Wnt pathway is a crucial step in the tumorigenesis of colorectal cancer (CRC). This study aimed to determine whether DNA methylation of Wnt pathway genes helps predict treatment response and survival in patients with metastatic or recurrent CRC. MATERIALS AND METHODS: W...

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Detalles Bibliográficos
Autores principales: Kim, Se Hyun, Park, Kyu Hyun, Shin, Sang Joon, Lee, Kang Young, Kim, Tae Il, Kim, Nam Kyu, Rha, Sun Young, Ahn, Joong Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990680/
https://www.ncbi.nlm.nih.gov/pubmed/29869456
http://dx.doi.org/10.3349/ymj.2018.59.5.588