Cargando…

Hsp90 Is Essential for Chl1-Mediated Chromosome Segregation and Sister Chromatid Cohesion

Recent studies have demonstrated that aberrant sister chromatid cohesion causes genomic instability and hence is responsible for the development of a tumor. The Chl1 (chromosome loss 1) protein (homolog of human ChlRl/DDX11 helicase) plays an essential role in the proper segregation of chromosomes d...

Descripción completa

Detalles Bibliográficos
Autores principales: Khurana, Nidhi, Bakshi, Sayan, Tabassum, Wahida, Bhattacharyya, Mrinal K., Bhattacharyya, Sunanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990887/
https://www.ncbi.nlm.nih.gov/pubmed/29875144
http://dx.doi.org/10.1128/mSphere.00225-18