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Capillary HILIC-MS: A New Tool for Sensitive Top-Down Proteomics

[Image: see text] Recent progress in top-down proteomics has driven the demand for chromatographic methods compatible with mass spectrometry (MS) that can separate intact proteins. Hydrophilic interaction liquid chromatography (HILIC) has recently shown good potential for the characterization of gly...

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Detalles Bibliográficos
Autores principales: Gargano, Andrea F.G., Roca, Liana S., Fellers, Ryan T., Bocxe, Max, Domínguez-Vega, Elena, Somsen, Govert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990932/
https://www.ncbi.nlm.nih.gov/pubmed/29722972
http://dx.doi.org/10.1021/acs.analchem.8b00382