Recent evidence that TADs and chromatin loops are dynamic structures

Mammalian genomes are folded into spatial domains, which regulate gene expression by modulating enhancer-promoter contacts. Here, we review recent studies on the structure and function of Topologically Associating Domains (TADs) and chromatin loops. We discuss how loop extrusion models can explain T...

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Detalles Bibliográficos
Autores principales: Hansen, Anders S., Cattoglio, Claudia, Darzacq, Xavier, Tjian, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990973/
https://www.ncbi.nlm.nih.gov/pubmed/29077530
http://dx.doi.org/10.1080/19491034.2017.1389365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990973/
https://www.ncbi.nlm.nih.gov/pubmed/29077530
http://dx.doi.org/10.1080/19491034.2017.1389365

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