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Development of a Rapid and Precise Reversed-phase High-performance Liquid Chromatography Method for Analysis of Docetaxel in Rat Plasma: Application in Single-dose Pharmacokinetic Studies of Folate-targeted Micelles Containing Docetaxel

BACKGROUND: A simple and sensitive reversed-phase high-performance liquid chromatography (HPLC) method based on liquid-liquid extraction was established and validated for determination of docetaxel (DTX) in plasma of rat. MATERIALS AND METHODS: Samples were spiked with paclitaxel as the internal sta...

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Detalles Bibliográficos
Autores principales: Taymouri, Somayeh, Varshosaz, Jaleh, Javanmard, Shaghayegh Haghjooy, Hassanzadeh, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991273/
https://www.ncbi.nlm.nih.gov/pubmed/29930916
http://dx.doi.org/10.4103/abr.abr_251_16