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Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia

Early-life adversity increases the risk for emotional disorders such as depression and schizophrenia. Anhedonia, thought to be a core feature of these disorders, is provoked by our naturalistic rodent model of childhood adversity (i.e., rearing pups for one week in cages with limited bedding and nes...

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Detalles Bibliográficos
Autores principales: Bolton, Jessica L., Ruiz, Christina M., Rismanchi, Neggy, Sanchez, Gissell A., Castillo, Erik, Huang, Jeff, Cross, Christopher, Baram, Tallie Z., Mahler, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991313/
https://www.ncbi.nlm.nih.gov/pubmed/29888304
http://dx.doi.org/10.1016/j.ynstr.2018.01.002