Reduced left ventricular dimension and function following early life stress: A thrifty phenotype hypothesis engendering risk for mood and anxiety disorders

BACKGROUND: Early life stress (ELS) in macaques in the form of insecure maternal attachment putatively induces epigenetic adaptations resulting in a “thrifty phenotype” throughout the life cycle. For instance, ELS induces persistent increases in insulin resistance, hippocampal and corpus callosum at...

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Detalles Bibliográficos
Autores principales: Coplan, Jeremy D., Rozenboym, Anna V., Fulton, Sasha L., Panthangi, Venkatesh, Tang, Jean, Thiramangalakdi, Lakshmi, Perera, Tarique D., Liu, Yang, Kamran, Haroon, Owens, Michael J., Nemeroff, Charles B., Rosenblum, Leonard A., Kral, John G., Salciccioli, Louis, Lazar, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991339/
https://www.ncbi.nlm.nih.gov/pubmed/29888314
http://dx.doi.org/10.1016/j.ynstr.2017.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991339/
https://www.ncbi.nlm.nih.gov/pubmed/29888314
http://dx.doi.org/10.1016/j.ynstr.2017.01.001

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