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Unsolved mysteries: How does lipid peroxidation cause ferroptosis?
Ferroptosis is a cell death process driven by damage to cell membranes and linked to numerous human diseases. Ferroptosis is caused by loss of activity of the key enzyme that is tasked with repairing oxidative damage to cell membranes—glutathione peroxidase 4 (GPX4). GPX4 normally removes the danger...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991413/ https://www.ncbi.nlm.nih.gov/pubmed/29795546 http://dx.doi.org/10.1371/journal.pbio.2006203 |