Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

Most active DNA replication origins are found within euchromatin, while origins within heterochromatin are often inactive or inhibited. In yeast, origin activity within heterochromatin is negatively controlled by the histone H4K16 deacetylase, Sir2, and at some heterochromatic loci also by the nucle...

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Detalles Bibliográficos
Autores principales: Hoggard, Timothy A., Chang, FuJung, Perry, Kelsey Rae, Subramanian, Sandya, Kenworthy, Jessica, Chueng, Julie, Shor, Erika, Hyland, Edel M., Boeke, Jef D., Weinreich, Michael, Fox, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991416/
https://www.ncbi.nlm.nih.gov/pubmed/29795547
http://dx.doi.org/10.1371/journal.pgen.1007418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991416/
https://www.ncbi.nlm.nih.gov/pubmed/29795547
http://dx.doi.org/10.1371/journal.pgen.1007418

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