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Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins
Most active DNA replication origins are found within euchromatin, while origins within heterochromatin are often inactive or inhibited. In yeast, origin activity within heterochromatin is negatively controlled by the histone H4K16 deacetylase, Sir2, and at some heterochromatic loci also by the nucle...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991416/ https://www.ncbi.nlm.nih.gov/pubmed/29795547 http://dx.doi.org/10.1371/journal.pgen.1007418 |