Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection

Pooled CRISPR screens based on lentiviral systems have been widely applied to identify the effect of gene knockout on cellular phenotype. Although many screens were successful, they also have the limitation that genes conferring mild phenotypes or those essential for growth can be overlooked, as eve...

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Detalles Bibliográficos
Autores principales: Kim, Heon Seok, Lee, Kyungjin, Kim, Seong-Jun, Cho, Sungchan, Shin, Hye Jin, Kim, Chonsaeng, Kim, Jin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991512/
https://www.ncbi.nlm.nih.gov/pubmed/29712754
http://dx.doi.org/10.1101/gr.230250.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991512/
https://www.ncbi.nlm.nih.gov/pubmed/29712754
http://dx.doi.org/10.1101/gr.230250.117

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