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Detection and analysis of ancient segmental duplications in mammalian genomes

Although segmental duplications (SDs) represent hotbeds for genomic rearrangements and emergence of new genes, there are still no easy-to-use tools for identifying SDs. Moreover, while most previous studies focused on recently emerged SDs, detection of ancient SDs remains an open problem. We develop...

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Detalles Bibliográficos
Autores principales: Pu, Lianrong, Lin, Yu, Pevzner, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991524/
https://www.ncbi.nlm.nih.gov/pubmed/29735604
http://dx.doi.org/10.1101/gr.228718.117