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Apoptosis induction in acute promyelocytic leukemia cells through upregulation of CEBPα by miR-182 blockage

MicroRNAs (miRNAs) involved in regulation of the genes. The CCAAT/enhancer-binding protein-α (CEBPα) is a crucial transcription factor for normal hematopoiesis and cell cycle that frequently disrupted in human acute myeloid leukemia (AML). The miR-182 up-regulation in several malignant diseases such...

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Detalles Bibliográficos
Autores principales: Sharifi, Mohammadreza, Fasihi-Ramandi, Mahdi, Sheikhi, Abdolkarim, Moridnia, Abbas, Saneipour, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991526/
https://www.ncbi.nlm.nih.gov/pubmed/29911120
http://dx.doi.org/10.22099/mbrc.2018.27625.1297