EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment

Suppression of HIV replication by antiretroviral therapy (ART) or host immunity can prevent AIDS but not other HIV-associated conditions including neurocognitive impairment (HIV-NCI). Pathogenesis in HIV-suppressed individuals has been attributed to reservoirs of latent-inducible virus in resting CD...

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Detalles Bibliográficos
Autores principales: Gu, Chao-Jiang, Borjabad, Alejandra, Hadas, Eran, Kelschenbach, Jennifer, Kim, Boe-Hyun, Chao, Wei, Arancio, Ottavio, Suh, Jin, Polsky, Bruce, McMillan, JoEllyn, Edagwa, Benson, Gendelman, Howard E., Potash, Mary Jane, Volsky, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991655/
https://www.ncbi.nlm.nih.gov/pubmed/29879225
http://dx.doi.org/10.1371/journal.ppat.1007061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991655/
https://www.ncbi.nlm.nih.gov/pubmed/29879225
http://dx.doi.org/10.1371/journal.ppat.1007061

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