Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

Protein tyrosine kinase 6 (PTK6, or BRK) is aberrantly expressed in breast cancers, and emerging as an oncogene that promotes tumor cell proliferation, migration and evasion. Both kinase-dependent and -independent functions of PTK6 in driving tumor growth have been described, therefore targeting PTK...

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Detalles Bibliográficos
Autores principales: Qiu, Luping, Levine, Kymberly, Gajiwala, Ketan S., Cronin, Ciarán N., Nagata, Asako, Johnson, Eric, Kraus, Michelle, Tatlock, John, Kania, Robert, Foley, Timothy, Sun, Shaoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991704/
https://www.ncbi.nlm.nih.gov/pubmed/29879184
http://dx.doi.org/10.1371/journal.pone.0198374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991704/
https://www.ncbi.nlm.nih.gov/pubmed/29879184
http://dx.doi.org/10.1371/journal.pone.0198374

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