A survey of genetic fetal-haemoglobin modifiers in Nigerian patients with sickle cell anaemia

Genetic variants at three quantitative trait loci (QTL) for fetal haemoglobin (HbF), BCL11A, HBS1L-MYB and the β-globin gene cluster, have attracted interest as potential targets of therapeutic strategies for HbF reactivation in sickle cell anaemia (SCA). We carried out the first systematic evaluati...

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Detalles Bibliográficos
Autores principales: Adeyemo, Titilope A., Ojewunmi, Oyesola O., Oyetunji, Idat A., Rooks, Helen, Rees, David C., Akinsulie, Adebola O., Akanmu, Alani S., Thein, Swee Lay, Menzel, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991720/
https://www.ncbi.nlm.nih.gov/pubmed/29879141
http://dx.doi.org/10.1371/journal.pone.0197927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991720/
https://www.ncbi.nlm.nih.gov/pubmed/29879141
http://dx.doi.org/10.1371/journal.pone.0197927

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