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Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice

The lack of dystrophin in Duchenne muscular dystrophy (DMD) compromises the integrity and function of muscle fibers. Skeletal muscles, except the diaphragm, do not undergo progressive degeneration in adult mdx mice due to compensatory mechanisms, including structural protein upregulation. New mouse...

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Detalles Bibliográficos
Autores principales: Boulanger Piette, Antoine, Hamoudi, Dounia, Marcadet, Laetitia, Kyomi Labelle, Frédérique, Ovidiu David, Rares, Bossé, Sabrina, Argaw, Anteneh, Frenette, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991729/
https://www.ncbi.nlm.nih.gov/pubmed/29879154
http://dx.doi.org/10.1371/journal.pone.0198408