Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila

Epigenetic alteration has been implicated in aging. However, the mechanism by which epigenetic change impacts aging remains to be understood. H3K27me3, a highly conserved histone modification signifying transcriptional repression, is marked and maintained by Polycomb Repressive Complexes (PRCs). Her...

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Detalles Bibliográficos
Autores principales: Ma, Zaijun, Wang, Hui, Cai, Yuping, Wang, Han, Niu, Kongyan, Wu, Xiaofen, Ma, Huanhuan, Yang, Yun, Tong, Wenhua, Liu, Feng, Liu, Zhandong, Zhang, Yaoyang, Liu, Rui, Zhu, Zheng-Jiang, Liu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991832/
https://www.ncbi.nlm.nih.gov/pubmed/29809154
http://dx.doi.org/10.7554/eLife.35368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991832/
https://www.ncbi.nlm.nih.gov/pubmed/29809154
http://dx.doi.org/10.7554/eLife.35368

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