A label-free approach to detect ligand binding to cell surface proteins in real time

Electrophysiological recordings allow for monitoring the operation of proteins with high temporal resolution down to the single molecule level. This technique has been exploited to track either ion flow arising from channel opening or the synchronized movement of charged residues and/or ions within...

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Detalles Bibliográficos
Autores principales: Burtscher, Verena, Hotka, Matej, Li, Yang, Freissmuth, Michael, Sandtner, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991833/
https://www.ncbi.nlm.nih.gov/pubmed/29697048
http://dx.doi.org/10.7554/eLife.34944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991833/
https://www.ncbi.nlm.nih.gov/pubmed/29697048
http://dx.doi.org/10.7554/eLife.34944

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