Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus

To enhance adenovirus-mediated oncolysis, different approaches that tackle the selectivity, tumor penetration, and spreading potential of oncolytic adenoviruses have been reported. We have previously demonstrated that insertion of the internalizing Arginine-Glycine-Aspartic (iRGD) tumor-penetrating...

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Detalles Bibliográficos
Autores principales: Al-Zaher, Ahmed Abdullah, Moreno, Rafael, Fajardo, Carlos Alberto, Arias-Badia, Marcel, Farrera, Martí, de Sostoa, Jana, Rojas, Luis Alfonso, Alemany, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991897/
https://www.ncbi.nlm.nih.gov/pubmed/29888319
http://dx.doi.org/10.1016/j.omto.2018.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991897/
https://www.ncbi.nlm.nih.gov/pubmed/29888319
http://dx.doi.org/10.1016/j.omto.2018.01.003

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