Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Pathological cardiac remodeling during heart failure is associated with higher levels of lipid peroxidation products and lower abundance of several aldehyde detoxification enzymes, including aldehyde dehydrogenase 2 (ALDH2). An emerging idea that could explain these findings concerns the role of ele...

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Detalles Bibliográficos
Autores principales: Dassanayaka, Sujith, Zheng, Yuting, Gibb, Andrew A., Cummins, Timothy D., McNally, Lindsey A., Brittian, Kenneth R., Jagatheesan, Ganapathy, Audam, Timothy N., Long, Bethany W., Brainard, Robert E., Jones, Steven P., Hill, Bradford G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991908/
https://www.ncbi.nlm.nih.gov/pubmed/29885625
http://dx.doi.org/10.1016/j.redox.2018.05.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991908/
https://www.ncbi.nlm.nih.gov/pubmed/29885625
http://dx.doi.org/10.1016/j.redox.2018.05.016

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