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Targeting skeletal endothelium to ameliorate bone loss

Recent studies have identified a specialized subset of CD31(hi)EMCN(hi) vascular endothelium that positively regulates bone formation. However, it remains unclear how CD31(hi)EMCN(hi) endothelium levels are coupled to anabolic bone formation. Mice with an osteoblast-specific deletion of Shn3, which...

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Detalles Bibliográficos
Autores principales: Xu, Ren, Yallowitz, Alisha, Qin, An, Wu, Zhuhao, Shin, Dong Yeon, Kim, Jung-Min, Debnath, Shawon, Ji, Gang, Bostrom, Mathias P., Yang, Xu, Zhang, Chao, Dong, Han, Kermani, Pouneh, Lalani, Sarfaraz, Li, Na, Liu, Yifang, Poulos, Michael G., Wach, Amanda, Zhang, Yi, Inoue, Kazuki, Di Lorenzo, Annarita, Zhao, Baohong, Butler, Jason M., Shim, Jae-Hyuck, Glimcher, Laurie H., Greenblatt, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992080/
https://www.ncbi.nlm.nih.gov/pubmed/29785024
http://dx.doi.org/10.1038/s41591-018-0020-z