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Targeting skeletal endothelium to ameliorate bone loss
Recent studies have identified a specialized subset of CD31(hi)EMCN(hi) vascular endothelium that positively regulates bone formation. However, it remains unclear how CD31(hi)EMCN(hi) endothelium levels are coupled to anabolic bone formation. Mice with an osteoblast-specific deletion of Shn3, which...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992080/ https://www.ncbi.nlm.nih.gov/pubmed/29785024 http://dx.doi.org/10.1038/s41591-018-0020-z |