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Heterocyclization of polarized system: synthesis, antioxidant and anti-inflammatory 4-(pyridin-3-yl)-6-(thiophen-2-yl) pyrimidine-2-thiol derivatives

BACKGROUND: Chalcones are intent in the daily diet as a favorable chemotherapeutic compound; on the other hand thiophene moiety is present in a large number of bioactive molecules having diverse biological efficiency. RESULTS: Our current goal is the synthesis of (E)-1-(pyridin-3-yl)-3-(thiophen-2-y...

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Detalles Bibliográficos
Autores principales: Shehab, Wesam S., Abdellattif, Magda H., Mouneir, Samar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992111/
https://www.ncbi.nlm.nih.gov/pubmed/29881977
http://dx.doi.org/10.1186/s13065-018-0437-y