Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus

Pancreastatin (PST) is an endogenous peptide which regulates glucose and lipid metabolism in liver and adipose tissues. In type 2 diabetic patients, PST level is high and plays a crucial role in the negative regulation of insulin sensitivity. Novel therapeutic agents are needed to treat the diabetes...

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Detalles Bibliográficos
Autores principales: Hossain, Zakir, Valicherla, Guru R., Gupta, Anand P., Syed, Anees A., Riyazuddin, Mohammed, Chandra, Sharat, Siddiqi, Mohammad I., Gayen, Jiaur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992141/
https://www.ncbi.nlm.nih.gov/pubmed/29880906
http://dx.doi.org/10.1038/s41598-018-27018-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992141/
https://www.ncbi.nlm.nih.gov/pubmed/29880906
http://dx.doi.org/10.1038/s41598-018-27018-8

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