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Novel interaction between Alzheimer’s disease-related protein presenilin 1 and glutamate transporter 1

Neuronal hyperactivity is one of the earliest events observed in Alzheimer’s disease (AD). Moreover, alterations in the expression of glutamate transporters have been reported to exacerbate amyloid pathology and cognitive deficits in transgenic AD mouse models. However, the molecular links between t...

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Detalles Bibliográficos
Autores principales: Zoltowska, Katarzyna Marta, Maesako, Masato, Meier, Joshua, Berezovska, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992168/
https://www.ncbi.nlm.nih.gov/pubmed/29880815
http://dx.doi.org/10.1038/s41598-018-26888-2