Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins

DNA is typically found as a double helix, however it must be separated into single strands during all phases of DNA metabolism; including transcription, replication, recombination and repair. Although recent breakthroughs have enabled the design of modular RNA- and double-stranded DNA-binding protei...

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Detalles Bibliográficos
Autores principales: Spåhr, Henrik, Chia, Tiongsun, Lingford, James P., Siira, Stefan J., Cohen, Scott B., Filipovska, Aleksandra, Rackham, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992170/
https://www.ncbi.nlm.nih.gov/pubmed/29880855
http://dx.doi.org/10.1038/s41467-018-04388-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992170/
https://www.ncbi.nlm.nih.gov/pubmed/29880855
http://dx.doi.org/10.1038/s41467-018-04388-1

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