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Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins
DNA is typically found as a double helix, however it must be separated into single strands during all phases of DNA metabolism; including transcription, replication, recombination and repair. Although recent breakthroughs have enabled the design of modular RNA- and double-stranded DNA-binding protei...
Autores principales: | Spåhr, Henrik, Chia, Tiongsun, Lingford, James P., Siira, Stefan J., Cohen, Scott B., Filipovska, Aleksandra, Rackham, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992170/ https://www.ncbi.nlm.nih.gov/pubmed/29880855 http://dx.doi.org/10.1038/s41467-018-04388-1 |
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