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Diffusive tail anchorage determines velocity and force produced by kinesin-14 between crosslinked microtubules

Form and function of the mitotic spindle depend on motor proteins that crosslink microtubules and move them relative to each other. Among these are kinesin-14s, such as Ncd, which interact with one microtubule via their non-processive motor domains and with another via their diffusive tail domains,...

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Detalles Bibliográficos
Autores principales: Lüdecke, Annemarie, Seidel, Anja-Maria, Braun, Marcus, Lansky, Zdenek, Diez, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992172/
https://www.ncbi.nlm.nih.gov/pubmed/29880831
http://dx.doi.org/10.1038/s41467-018-04656-0