Pyrimidine synthesis inhibition enhances cutaneous defenses against antibiotic resistant bacteria through activation of NOD2 signaling

Multidrug-resistant bacterial strains are a rapidly emerging healthcare threat; therefore it is critical to develop new therapies to combat these organisms. Prior antibacterial strategies directly target pathogen growth or viability. Host-directed strategies to increase antimicrobial defenses may be...

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Detalles Bibliográficos
Autores principales: Jatana, Samreen, Homer, Craig R., Madajka, Maria, Ponti, András K., Kabi, Amrita, Papay, Francis, McDonald, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992176/
https://www.ncbi.nlm.nih.gov/pubmed/29880914
http://dx.doi.org/10.1038/s41598-018-27012-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992176/
https://www.ncbi.nlm.nih.gov/pubmed/29880914
http://dx.doi.org/10.1038/s41598-018-27012-0

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