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The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death

Cancer cells rewire their metabolism to satisfy the demands of uncontrolled proliferation and survival. The reprogramming of lipid metabolism supports tumor growth, metastasis, and therapy-resistance. Therefore, targeting lipid metabolic reprogramming is a potential cancer treatment strategy. We rec...

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Detalles Bibliográficos
Autores principales: Liu, Ge, Wang, Kai, Kuang, Shan, Cao, Ruobing, Bao, Li, Liu, Rui, Liu, Hongwei, Sun, Chaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992186/
https://www.ncbi.nlm.nih.gov/pubmed/29880886
http://dx.doi.org/10.1038/s41419-018-0731-6