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miR-16-5p inhibits chordoma cell proliferation, invasion and metastasis by targeting Smad3

Aberrantly expressed miRNAs play a crucial role in the development of multiple cancer types, including chordoma. However, the detailed molecular mechanisms are unclear and need to be elucidated. In this study, miRNAs were screened by miRNA array analysis and then confirmed by real-time PCR analysis....

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Detalles Bibliográficos
Autores principales: Zhang, Hongliang, Yang, Kang, Ren, Tingting, Huang, Yi, Tang, Xiaodong, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992191/
https://www.ncbi.nlm.nih.gov/pubmed/29880900
http://dx.doi.org/10.1038/s41419-018-0738-z