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miR-16-5p inhibits chordoma cell proliferation, invasion and metastasis by targeting Smad3
Aberrantly expressed miRNAs play a crucial role in the development of multiple cancer types, including chordoma. However, the detailed molecular mechanisms are unclear and need to be elucidated. In this study, miRNAs were screened by miRNA array analysis and then confirmed by real-time PCR analysis....
Autores principales: | Zhang, Hongliang, Yang, Kang, Ren, Tingting, Huang, Yi, Tang, Xiaodong, Guo, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992191/ https://www.ncbi.nlm.nih.gov/pubmed/29880900 http://dx.doi.org/10.1038/s41419-018-0738-z |
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