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Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson’s disease

MiRNAs, a group of powerful modulator of gene expression, participate in multiple cellular processes under physiological and pathological conditions. Emerging evidence shows that Drosha, which controls the initial step in canonical miRNA biogenesis, is involved in modulating cell survival and death...

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Detalles Bibliográficos
Autores principales: Wang, Ronglin, Lu, Fangfang, Zhu, Gang, Feng, Dayun, Nie, Tiejian, Tao, Kai, Yang, Shaosong, Lei, Jie, Huang, Lu, Mao, Zixu, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992196/
https://www.ncbi.nlm.nih.gov/pubmed/29880811
http://dx.doi.org/10.1038/s41419-018-0716-5