Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension

Background: Pulmonary hypertension (PH) is a devastating and progressive disease characterized by excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) and remodeling of the lung vasculature. Adenosine signaling through the ADORA2B receptor has previously been implicated in diseas...

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Detalles Bibliográficos
Autores principales: Mertens, Tinne C. J., Hanmandlu, Ankit, Tu, Ly, Phan, Carole, Collum, Scott D., Chen, Ning-Yuan, Weng, Tingting, Davies, Jonathan, Liu, Chen, Eltzschig, Holger K., Jyothula, Soma S. K., Rajagopal, Keshava, Xia, Yang, Guha, Ashrith, Bruckner, Brian A., Blackburn, Michael R., Guignabert, Christophe, Karmouty-Quintana, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992271/
https://www.ncbi.nlm.nih.gov/pubmed/29910735
http://dx.doi.org/10.3389/fphys.2018.00555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992271/
https://www.ncbi.nlm.nih.gov/pubmed/29910735
http://dx.doi.org/10.3389/fphys.2018.00555

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